The ingredients of BIKE Granule are all native trueborn medicine of the best quality and effect from traditional place of origin and natural wild medicine treasury in forests of GuiZhou , and it is natural, non-polluted, non-toxic and nuisance free medicinal materials with characteristics of long history, proper places of origin, excellent varieties, high output, dainty processing, and wonder curative effects.

After long term toxin testing of BIKE Granule, the quantity the little mouse had taken was equal to 60g/kg, after 7 days observation, the little mouse was active, smooth in fur, normal in diet. There were no symptoms or death appeared, and the medicine had no impact on blood picture, functions of liver and kidneys, and biochemical index. After stopping taking medicines for 14 days, there were still not any abnormal indications. There were no abnormal indications in the two pathologic testing.

It is proved that BIKE Granule has no toxic and side effects after clinical observations of 400 rheumatic patients. According to 4 years of following inspection about toxic and side effects carried on by quality inspection department, there were no bad feedbacks from market or inspection centers of user, so the safety of this medicine is obvious.